Polio
We make grants to partners and contribute technical and financial resources to develop more effective vaccines, expanding routine immunizations, improve polio surveillance and outbreak response, and more.
Learn moreEnding infectious diseases
A world without deadly infectious diseases
Today, we are closer than ever to wiping out some of world’s deadliest diseases for good. In the coming years and decades, we could eradicate polio and malaria and bring diseases like tuberculosis and HIV under control as manageable conditions.
Why ending infectious diseases matters:
- Infectious diseases still kill more than 10 million people a year and make hundreds of millions of people sick
- Today, we are closer than ever to wiping out some of these diseases for good.
Our goal is to ensure the next generation grows up safe from deadly disease.
How we work to end infectious diseases
Malaria
We have devoted resources and expertise to a relentless pursuit of malaria eradication. We support efforts to reduce the burden of malaria, accelerate progress toward eradication, and get ahead of drug and insecticide resistance.
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Tuberculosis
Our tuberculosis team aims to address key gaps along the TB care pathway through new approaches to protecting against infection, preventing progression from infection to disease, and improving diagnosis and treatment.
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HIV
We focus our efforts in some of the countries hardest hit by HIV in sub-Saharan Africa, particularly among populations that are at greatest risk of infection, including adolescent girls and young women.
Learn moreCan you beat the mosquitoes?
Navigate real-world challenges, discover the innovations and tools helping protect families, and work to eradicate malaria from your community.
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The malaria researcher who won’t quit: Dr. Faith Osier
Dr. Faith Osier watched malaria devastate communities across Kenya. Now she’s building the science to stop it.
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The peer coaching program getting men back on HIV/AIDS treatment in South Africa
In South Africa, men face unique barriers to staying on HIV treatment. Coach Mpilo — a brotherhood of peer coaches — is changing that.
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The hidden journey of a vaccine
This explainer shows the complete lifecycle of vaccine development—from research and testing to manufacturing and delivery.
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The TB epidemic at a turning point
As TB overtakes COVID as the deadliest global disease, this article explores how key lessons can inform new TB vaccine development led by scientific leaders in Africa.
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Three takeaways from the 2025 Progress Report
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What can the world learn from Cabo Verde’s fight against malaria?
Cabo Verde’s fight against malaria—powered by local leadership and Global Fund support—shows how partnership can eliminate disease worldwide.
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One man’s mission to protect Liberia’s children from polio
Learn how vaccines helped stop a polio outbreak and protected millions of children across Liberia.
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The Global Fund works—these stories remind us why it’s essential
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Why two American teens want you to know about PEPFAR
From home visits to storytelling, a family documents how PEPFAR enables treatment, work, and stability for women and children in Nairobi.
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